{"id":786882,"date":"2026-02-17T21:02:12","date_gmt":"2026-02-17T20:02:12","guid":{"rendered":"https:\/\/www.hashtag.al\/?p=786882"},"modified":"2026-02-17T21:02:12","modified_gmt":"2026-02-17T20:02:12","slug":"nje-analize-e-thjeshte-gjaku-mund-te-ndihmoje-ne-diagnostikimin-e-hershem-te-mielomes-se-shumefishte","status":"publish","type":"post","link":"https:\/\/www.hashtag.al\/index.php\/2026\/02\/17\/nje-analize-e-thjeshte-gjaku-mund-te-ndihmoje-ne-diagnostikimin-e-hershem-te-mielomes-se-shumefishte\/","title":{"rendered":"Nj\u00eb analiz\u00eb e thjesht\u00eb gjaku mund t\u00eb ndihmoj\u00eb n\u00eb diagnostikimin e hersh\u00ebm t\u00eb mielom\u00ebs s\u00eb shum\u00ebfisht\u00eb","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"

\"\"<\/p>\n

Nj\u00eb nga fushat m\u00eb intriguese sot \u00ebsht\u00eb diagnoza e hershme \u2014 identifikimi i ndryshimeve delikate n\u00eb trup n\u00eb nj\u00eb stad kur personi ndihet plot\u00ebsisht i sh\u00ebndetsh\u00ebm. Nj\u00eb studim i ri n\u00eb k\u00ebrkimet mbi kancerin e gjakut tregon se si nj\u00eb analiz\u00eb e thjesht\u00eb gjaku mund t\u00eb hap\u00eb nj\u00eb dritare mund\u00ebsie p\u00ebr monitorim, parandalim dhe trajtim t\u00eb personalizuar.<\/span><\/p>\n

Nj\u00eb studim i quajtur PROMISE nisi n\u00eb Institutin e Kancerit “Dana-Farber” n\u00eb Universitetin e Harvardit n\u00eb SHBA dhe synon t\u00eb zbuloj\u00eb nj\u00eb s\u00ebmundje t\u00eb gjakut t\u00eb njohur si mieloma e shum\u00ebfisht\u00eb n\u00eb stadet e saj beninje, shum\u00eb koh\u00eb para se t\u00eb shfaqen simptomat.<\/span><\/p>\n

\u00c7far\u00eb \u00ebsht\u00eb mieloma e shum\u00ebfisht\u00eb?<\/strong><\/span><\/p>\n

Mieloma \u00ebsht\u00eb nj\u00eb kancer i qelizave plakmatike n\u00eb gjak \u2014 qelizat n\u00eb palc\u00ebn e kockave p\u00ebrgjegj\u00ebse p\u00ebr prodhimin e antitrupave dhe mbrojtjen e trupit nga infeksionet. Kur k\u00ebto qeliza b\u00ebhen kanceroze, ato shumohen n\u00eb m\u00ebnyr\u00eb t\u00eb pakontrolluar dhe d\u00ebmtojn\u00eb kockat, veshkat dhe prodhimin normal t\u00eb gjakut.<\/span><\/p>\n

Tani dihet se pothuajse \u00e7do pacient me mielom\u00eb e ka nisur me nj\u00eb gjendje t\u00eb qet\u00eb, beninje dhe parakanceroze t\u00eb quajtur MGUS (Gamapatia Monoklonale me R\u00ebnd\u00ebsi t\u00eb Pap\u00ebrcaktuar). N\u00eb k\u00ebt\u00eb gjendje, qelizat plakmatike prodhojn\u00eb nj\u00eb sasi t\u00eb vog\u00ebl proteine jonormale, por pa d\u00ebmtime t\u00eb organeve apo simptoma. MGUS mund t\u00eb vazhdoj\u00eb p\u00ebr shum\u00eb vite para se t\u00eb p\u00ebrparoj\u00eb n\u00eb s\u00ebmundje aktive. Nj\u00eb stad nd\u00ebrmjet\u00ebs m\u00eb i avancuar, i njohur si “smoldering myeloma” (mieloma e fshehur), p\u00ebrfshin nj\u00eb barr\u00eb m\u00eb t\u00eb lart\u00eb t\u00eb s\u00ebmundjes dhe nj\u00eb rrezik duksh\u00ebm m\u00eb t\u00eb madh p\u00ebr t’u shnd\u00ebrruar n\u00eb s\u00ebmundje aktive.<\/span><\/p>\n

\"\"<\/p>\n

Gjetjet e studimit n\u00eb Izrael<\/span><\/strong><\/p>\n

Q\u00ebllimi i studimit, i udh\u00ebhequr n\u00eb Izrael nga Qendra Mjek\u00ebsore Sourasky e Tel Avivit (Ichilov), \u00ebsht\u00eb t\u00eb identifikoj\u00eb individ\u00ebt e sh\u00ebndetsh\u00ebm n\u00eb t\u00eb dyja stadet: at\u00eb beninj dhe at\u00eb “smoldering”.<\/span><\/p>\n

Studimi fokusohet te t\u00eb af\u00ebrmit e shkall\u00ebs s\u00eb par\u00eb t\u00eb pacient\u00ebve me mielom\u00eb, t\u00eb cil\u00ebt rezulton se p\u00ebrballen me nj\u00eb rrezik m\u00eb t\u00eb lart\u00eb se popullata e p\u00ebrgjithshme. Jan\u00eb rekrutuar 228 t\u00eb af\u00ebrm t\u00eb sh\u00ebndetsh\u00ebm dhe asimptomatik\u00eb, gjysma e tyre n\u00ebn mosh\u00ebn 50 vje\u00e7. Pjes\u00ebmarr\u00ebsit iu n\u00ebnshtruan analizave t\u00eb gjakut shum\u00eb t\u00eb avancuara dhe t\u00eb ndjeshme, t\u00eb afta p\u00ebr t\u00eb zbuluar sasi minimale t\u00eb protein\u00ebs jonormale \u2014 shum\u00eb koh\u00eb p\u00ebrpara se analizat standarde t\u00eb gjakut t\u00eb identifikonin di\u00e7ka t\u00eb pazakont\u00eb.<\/span><\/p>\n

Pavar\u00ebsisht mosh\u00ebs s\u00eb tyre relativisht t\u00eb re, rreth 11.4% e pjes\u00ebmarr\u00ebsve rezultuan se mbanin gjendjen parakanceroze \u2014 nj\u00eb shkall\u00eb duksh\u00ebm m\u00eb e lart\u00eb se n\u00eb popullat\u00ebn e p\u00ebrgjithshme, ku p\u00ebrhapja \u00ebsht\u00eb rreth 3% te personat mbi 50 vje\u00e7.<\/span><\/p>\n

\"\"

Profesoresha Irit Avivi \u00ebsht\u00eb drejtoresh\u00eb e Divizionit t\u00eb Hematologjis\u00eb n\u00eb Qendr\u00ebn Mjek\u00ebsore Sourasky t\u00eb Tel Aviv-Spitali Ichilov<\/span><\/em><\/p><\/div>\n

Testi inovativ epigjenetik<\/span><\/strong><\/p>\n

Nj\u00eb nga gjetjet kryesore p\u00ebrfshin nj\u00eb test inovativ epigjenetik. Tradicionalisht, dallimi midis MGUS, mielom\u00ebs “smoldering” dhe asaj aktive k\u00ebrkonte nj\u00eb biopsi t\u00eb palc\u00ebs s\u00eb kockave \u2014 nj\u00eb procedur\u00eb invazive dhe e pak\u00ebndshme.<\/span><\/p>\n

Megjithat\u00eb, testi epigjenetik nuk ekzaminon vet\u00eb ADN-n\u00eb, por “\u00e7el\u00ebsat” q\u00eb ndezin ose fikin gjenet defektive. Qelizat e s\u00ebmura kan\u00eb nj\u00eb n\u00ebnshkrim unik epigjenetik q\u00eb mund t\u00eb zbulohet n\u00eb rrjedh\u00ebn e gjakut. P\u00ebrmes k\u00ebtij testi t\u00eb thjesht\u00eb, \u00ebsht\u00eb e mundur jo vet\u00ebm t\u00eb identifikohet prania e s\u00ebmundjes, por edhe t\u00eb b\u00ebhet dallimi me sakt\u00ebsi t\u00eb lart\u00eb midis stadeve.<\/span><\/p>\n

N\u00eb t\u00eb kaluar\u00ebn, qasja ndaj mielom\u00ebs “smoldering” ishte “prit dhe shiko” \u2014 monitorimi i pacient\u00ebve derisa t\u00eb zhvilloheshin simptomat. Studimet e reja tregojn\u00eb se nd\u00ebrhyrja e hershme me trajtime relativisht t\u00eb lehta mund t\u00eb parandaloj\u00eb d\u00ebmtimin e pakthyesh\u00ebm t\u00eb organeve dhe n\u00eb disa raste madje t\u00eb zgjas\u00eb jet\u00ebgjat\u00ebsin\u00eb.<\/span><\/p>\n

Ne q\u00ebndrojm\u00eb n\u00eb pragun e nj\u00eb epoke t\u00eb re: kanceri i gjakut mund t\u00eb identifikohet nd\u00ebrsa trupi ende ndihet plot\u00ebsisht i sh\u00ebndetsh\u00ebm, pacient\u00ebt mund t\u00eb monitorohen nga af\u00ebr dhe d\u00ebmtimet fizike mund t\u00eb parandalohen, shkruan Ynet<\/a>.<\/span><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"

Nj\u00eb nga fushat m\u00eb intriguese sot \u00ebsht\u00eb diagnoza e hershme \u2014 identifikimi i ndryshimeve delikate n\u00eb trup n\u00eb nj\u00eb stad kur personi ndihet plot\u00ebsisht i sh\u00ebndetsh\u00ebm. Nj\u00eb studim i ri n\u00eb k\u00ebrkimet mbi kancerin e gjakut tregon se si nj\u00eb analiz\u00eb e thjesht\u00eb gjaku mund t\u00eb hap\u00eb nj\u00eb dritare mund\u00ebsie p\u00ebr monitorim, parandalim dhe trajtim […]<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":51,"featured_media":786883,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[53],"tags":[],"class_list":["post-786882","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fast-foodi"],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/786882","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/users\/51"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/comments?post=786882"}],"version-history":[{"count":1,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/786882\/revisions"}],"predecessor-version":[{"id":786886,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/786882\/revisions\/786886"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media\/786883"}],"wp:attachment":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media?parent=786882"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/categories?post=786882"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/tags?post=786882"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}