![\"\"](\"https:\/\/www.hashtag.al\/wp-content\/uploads\/2026\/02\/kancewr.jpg\")
<\/p>\n<\/p>\n
Nj\u00eb zbulim i ri shkencor n\u00eb kuptimin e patologjis\u00eb s\u00eb glioblastom\u00ebs \u2014 forma m\u00eb e zakonshme dhe nj\u00ebkoh\u00ebsisht m\u00eb agresive e kancerit t\u00eb trurit, e cila aktualisht konsiderohet e pash\u00ebrueshme \u2014 ka hapur perspektiva t\u00eb reja p\u00ebr zhvillimin e nj\u00eb trajtimi t\u00eb ardhsh\u00ebm q\u00eb, n\u00eb parim, mund t\u00eb jet\u00eb po aq i thjesht\u00eb sa marrja e nj\u00eb pilule.<\/span><\/p>\n Vet\u00ebm n\u00eb Shtetet e Bashkuara, \u00e7do vit m\u00eb shum\u00eb se 14,000 persona diagnostikohen me glioblastom\u00eb. Ky tumor i trurit \u00ebsht\u00eb jasht\u00ebzakonisht agresiv, i paparashikuesh\u00ebm dhe rezistent ndaj trajtimeve ekzistuese. Pacient\u00ebt e diagnostikuar rishtazi jetojn\u00eb mesatarisht vet\u00ebm 12 deri n\u00eb 18 muaj, edhe me trajtim; pa nd\u00ebrhyrje mjek\u00ebsore, kjo koh\u00eb do t\u00eb ishte edhe m\u00eb e shkurt\u00ebr. Vet\u00ebm rreth 5% e pacient\u00ebve arrijn\u00eb t\u00eb mbijetojn\u00eb pes\u00eb vjet pas diagnoz\u00ebs.<\/span><\/p>\n \u201cGlioblastoma \u00ebsht\u00eb nj\u00eb s\u00ebmundje shkat\u00ebrruese. N\u00eb praktik\u00eb, nuk ekziston asnj\u00eb terapi v\u00ebrtet efektive,\u201d u shpreh Hui Li, studiues n\u00eb Departamentin e Patologjis\u00eb n\u00eb Shkoll\u00ebn e Mjek\u00ebsis\u00eb t\u00eb Universitetit t\u00eb Virxhinias, n\u00eb nj\u00eb deklarat\u00eb t\u00eb publikuar k\u00ebt\u00eb jav\u00eb. Megjithat\u00eb, n\u00eb vitin 2020, Li dhe ekipi i tij hodh\u00ebn nj\u00eb hap t\u00eb r\u00ebnd\u00ebsish\u00ebm p\u00ebrpara, duke identifikuar nj\u00eb t\u00eb ashtuquajtur onkogjen \u2014 nj\u00eb gjen q\u00eb nxit dhe mban gjall\u00eb zhvillimin e glioblastom\u00ebs.<\/span><\/p>\n \u201cOnkogjeni i ri q\u00eb kemi zbuluar premton t\u00eb jet\u00eb \u2018thembra e Akilit\u2019 e glioblastom\u00ebs,\u201d deklaroi Li n\u00eb at\u00eb koh\u00eb. \u201cSh\u00ebnjestrimi specifik i tij mund t\u00eb p\u00ebrfaq\u00ebsoj\u00eb nj\u00eb qasje shum\u00eb efektive p\u00ebr trajtimin e k\u00ebsaj s\u00ebmundjeje.\u201d<\/span><\/p>\n Tani, ekipi ka b\u00ebr\u00eb t\u00eb ditur nj\u00eb hap t\u00eb ri dhe vendimtar drejt zhvillimit t\u00eb nj\u00eb trajtimi, apo potencialisht edhe nj\u00eb kure: identifikimin e nj\u00eb molekule specifike q\u00eb \u00ebsht\u00eb n\u00eb gjendje t\u00eb bllokoj\u00eb aktivitetin e k\u00ebtij onkogjeni. N\u00eb studimet e kryera te minjt\u00eb, kjo molekul\u00eb ka treguar se \u00ebsht\u00eb e aft\u00eb t\u00eb shkat\u00ebrroj\u00eb qelizat e glioblastom\u00ebs pa d\u00ebmtuar indet e sh\u00ebndetshme p\u00ebrreth.<\/span><\/p>\n \u201cRisia q\u00ebndron n\u00eb faktin se ne po sh\u00ebnjestrojm\u00eb nj\u00eb protein\u00eb nga e cila qelizat e glioblastom\u00ebs varen n\u00eb m\u00ebnyr\u00eb unike,\u201d shpjegoi Li. \u201cDhe k\u00ebt\u00eb po e b\u00ebjm\u00eb me nj\u00eb molekul\u00eb t\u00eb vog\u00ebl, e cila tregon aktivitet t\u00eb qart\u00eb in vivo. Sipas dijenis\u00eb son\u00eb, kjo rrug\u00eb biologjike nuk \u00ebsht\u00eb shfryt\u00ebzuar m\u00eb par\u00eb p\u00ebr q\u00ebllime terapeutike.\u201d<\/span><\/p>\n Megjithat\u00eb, ky zbulim nuk p\u00ebrb\u00ebn ende nj\u00eb trajtim t\u00eb gatsh\u00ebm p\u00ebr p\u00ebrdorim klinik. P\u00ebrpara se ky p\u00ebrb\u00ebr\u00ebs i ri t\u00eb shnd\u00ebrrohet n\u00eb nj\u00eb medikament t\u00eb disponuesh\u00ebm p\u00ebr pacient\u00ebt, ai duhet t\u00eb kaloj\u00eb n\u00ebp\u00ebr nj\u00eb seri provash klinike rigoroze dhe testimesh t\u00eb m\u00ebtejshme. Madje, edhe p\u00ebrpara faz\u00ebs klinike, nevojiten studime shtes\u00eb teorike p\u00ebr t\u00eb kuptuar plot\u00ebsisht se si mund t\u00eb shfryt\u00ebzohet n\u00eb m\u00ebnyr\u00ebn m\u00eb efektive.<\/span><\/p>\n Edhe k\u00ebshtu, n\u00eb nivel konceptual, ky zbulim shihet si jasht\u00ebzakonisht premtues. Molekula n\u00eb fjal\u00eb \u00ebsht\u00eb e aft\u00eb t\u00eb kaloj\u00eb barrier\u00ebn gjak\u2013tru \u2014 nj\u00eb penges\u00eb madhore q\u00eb ka kufizuar shum\u00eb trajtime t\u00eb tjera t\u00eb mundshme p\u00ebr kanceret e trurit \u2014 dhe, pasi arrin n\u00eb tru, duket se vepron n\u00eb m\u00ebnyr\u00eb selektive duke shkat\u00ebrruar vet\u00ebm qelizat kancerogjene. Sipas studiuesve, ajo potencialisht mund t\u00eb administrohet edhe n\u00eb form\u00ebn e nj\u00eb pilule orale, shkruan Ifl<\/a><\/span>.<\/span><\/p>\n \u201cPacient\u00ebt me glioblastom\u00eb kan\u00eb nj\u00eb nevoj\u00eb urgjente p\u00ebr opsione m\u00eb t\u00eb mira trajtimi,\u201d theksoi Li. \u201cTerapia standarde ka mbetur pothuajse e pandryshuar p\u00ebr dekada t\u00eb t\u00ebra, dhe normat e mbijetes\u00ebs vazhdojn\u00eb t\u00eb jen\u00eb d\u00ebshp\u00ebruese.\u201d<\/span><\/p>\n \u201cQ\u00ebllimi yn\u00eb,\u201d p\u00ebrfundoi ai, \u201c\u00ebsht\u00eb t\u00eb sjellim n\u00eb praktik\u00ebn klinike nj\u00eb mekaniz\u00ebm veprimi krejt\u00ebsisht t\u00eb ri \u2014 nj\u00eb mekaniz\u00ebm q\u00eb sh\u00ebnjestron nj\u00eb dob\u00ebsi themelore n\u00eb biologjin\u00eb e glioblastom\u00ebs.\u201d<\/span><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":" Nj\u00eb zbulim i ri shkencor n\u00eb kuptimin e patologjis\u00eb s\u00eb glioblastom\u00ebs \u2014 forma m\u00eb e zakonshme dhe nj\u00ebkoh\u00ebsisht m\u00eb agresive e kancerit t\u00eb trurit, e cila aktualisht konsiderohet e pash\u00ebrueshme \u2014 ka hapur perspektiva t\u00eb reja p\u00ebr zhvillimin e nj\u00eb trajtimi t\u00eb ardhsh\u00ebm q\u00eb, n\u00eb parim, mund t\u00eb jet\u00eb po aq i thjesht\u00eb sa marrja […]<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":51,"featured_media":785305,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[53],"tags":[],"class_list":["post-785304","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fast-foodi"],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/785304","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/users\/51"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/comments?post=785304"}],"version-history":[{"count":99999,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/785304\/revisions"}],"predecessor-version":[{"id":785306,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/785304\/revisions\/785306"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media\/785305"}],"wp:attachment":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media?parent=785304"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/categories?post=785304"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/tags?post=785304"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}