{"id":772777,"date":"2025-11-21T22:09:15","date_gmt":"2025-11-21T21:09:15","guid":{"rendered":"https:\/\/www.hashtag.al\/?p=772777"},"modified":"2025-11-21T22:09:15","modified_gmt":"2025-11-21T21:09:15","slug":"nje-pilule-e-re-ul-kolesterolin-me-60-thote-studimi","status":"publish","type":"post","link":"https:\/\/www.hashtag.al\/index.php\/2025\/11\/21\/nje-pilule-e-re-ul-kolesterolin-me-60-thote-studimi\/","title":{"rendered":"Nj\u00eb pilul\u00eb e re ul kolesterolin me 60%, thot\u00eb studimi","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"

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\nNj\u00eb pilul\u00eb e re ditore mund t\u00eb ul\u00eb nivelin e kolesterolit \u201ct\u00eb keq\u201d (LDL) deri n\u00eb 60%, sipas nj\u00eb studimi t\u00eb publikuar k\u00ebt\u00eb jav\u00eb n\u00eb revist\u00ebn JAMA, <\/em>t\u00eb cituar nga Fox News<\/a><\/span>.<\/span><\/p>\n

Medikamenti, i quajtur Enlicitide dhe i zhvilluar nga kompania Merck, tregoi rezultate t\u00eb jasht\u00ebzakonshme n\u00eb nj\u00eb prov\u00eb klinike globale t\u00eb udh\u00ebhequr nga Dr. Christie M. Ballantyne i Texas Heart Institute.<\/span><\/p>\n

Studimi u zhvillua n\u00eb 59 qendra mjek\u00ebsore n\u00eb 17 vende dhe p\u00ebrfshiu 303 t\u00eb rritur me nj\u00eb gjendje gjenetike t\u00eb quajtur Hiperlipidemia Familjare Heterozigote<\/em> (HeFH), e cila rrit LDL-n\u00eb dhe rrezikun p\u00ebr s\u00ebmundje t\u00eb hershme t\u00eb zemr\u00ebs.<\/span><\/p>\n

T\u00eb gjith\u00eb pjes\u00ebmarr\u00ebsit ishin duke marr\u00eb edhe terapi t\u00eb tjera p\u00ebr uljen e lipideve, por nivelet e tyre t\u00eb kolesterolit mbeteshin mbi norm\u00ebn e synuar.<\/span><\/p>\n

Rezultatet e prov\u00ebs klinike<\/span><\/h3>\n

Pjes\u00ebmarr\u00ebsit mor\u00ebn rast\u00ebsisht ose 20 mg Enlicitide n\u00eb dit\u00eb, ose nj\u00eb placebo.<\/span><\/p>\n

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    Pas 24 jav\u00ebsh, grupi q\u00eb mori Enlicitide sh\u00ebnoi nj\u00eb ulje mesatare prej 58% t\u00eb LDL.<\/span><\/p>\n<\/li>\n

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    Grupi me placebo nuk pati asnj\u00eb ndryshim t\u00eb r\u00ebnd\u00ebsish\u00ebm.<\/span><\/p>\n<\/li>\n

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    Efekti mbeti i q\u00ebndruesh\u00ebm deri n\u00eb jav\u00ebn e 52-t\u00eb, ku grupi q\u00eb mori ila\u00e7in ruajti nj\u00eb ulje prej rreth 55%.<\/span><\/p>\n<\/li>\n<\/ul>\n

    Gjithashtu u vun\u00eb re p\u00ebrmir\u00ebsime t\u00eb tjera:<\/span><\/p>\n

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      Non-HDL kolesteroli ra me 52%<\/span><\/p>\n<\/li>\n

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      Apolipoproteina B me 48%<\/span><\/p>\n<\/li>\n

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      Lipoproteina(a) me gati 25%<\/span><\/p>\n<\/li>\n<\/ul>\n

      Rreth 97% e pacient\u00ebve e p\u00ebrfunduan studimin dhe efektet an\u00ebsore ishin pothuajse t\u00eb nj\u00ebjta mes t\u00eb dy grupeve, kryesisht t\u00eb lehta dhe t\u00eb p\u00ebrkohshme si dhimbje koke apo simptoma gripi.<\/span><\/p>\n

      \u00c7far\u00eb e b\u00ebn k\u00ebt\u00eb ila\u00e7 t\u00eb r\u00ebnd\u00ebsish\u00ebm?<\/span><\/h3>\n

      HeFH prek rreth 1 n\u00eb 250 persona n\u00eb bot\u00eb, dhe shum\u00eb pacient\u00eb nuk arrijn\u00eb t\u00eb kontrollojn\u00eb kolesterolin edhe me terapi intensive. Aktualisht, rezultatet m\u00eb t\u00eb ngjashme jepen nga injeksionet PCSK9, t\u00eb cilat aplikohen \u00e7do disa jav\u00eb.<\/span><\/p>\n

      Enlicitide ofron nj\u00eb alternativ\u00eb m\u00eb t\u00eb thjesht\u00eb: nj\u00eb pilul\u00eb e vetme n\u00eb dit\u00eb.<\/span><\/p>\n

      Kufizimet e studimit<\/span><\/h3>\n

      Studiuesit theksojn\u00eb se:<\/span><\/p>\n

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        Studimi mat vet\u00ebm uljen e kolesterolit, jo ndikimin real n\u00eb sulme n\u00eb zem\u00ebr, goditje apo vdekshm\u00ebri \u2014 k\u00ebto k\u00ebrkojn\u00eb prova m\u00eb t\u00eb m\u00ebdha.<\/span><\/p>\n<\/li>\n

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        P\u00ebrfshiu vet\u00ebm persona me HeFH q\u00eb tashm\u00eb merrnin trajtime t\u00eb tjera.<\/span><\/p>\n<\/li>\n

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        Siguria afatgjat\u00eb e ila\u00e7it ende nuk \u00ebsht\u00eb provuar.<\/span><\/p>\n<\/li>\n<\/ul>\n

        Kompania Merck pritet t\u00eb komentoj\u00eb mbi k\u00ebto rezultate n\u00eb vijim.<\/span><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"

        Nj\u00eb pilul\u00eb e re ditore mund t\u00eb ul\u00eb nivelin e kolesterolit \u201ct\u00eb keq\u201d (LDL) deri n\u00eb 60%, sipas nj\u00eb studimi t\u00eb publikuar k\u00ebt\u00eb jav\u00eb n\u00eb revist\u00ebn JAMA, t\u00eb cituar nga Fox News. Medikamenti, i quajtur Enlicitide dhe i zhvilluar nga kompania Merck, tregoi rezultate t\u00eb jasht\u00ebzakonshme n\u00eb nj\u00eb prov\u00eb klinike globale t\u00eb udh\u00ebhequr nga Dr. […]<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":32,"featured_media":772778,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[53],"tags":[],"class_list":["post-772777","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fast-foodi"],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/772777","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/users\/32"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/comments?post=772777"}],"version-history":[{"count":99999,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/772777\/revisions"}],"predecessor-version":[{"id":772779,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/772777\/revisions\/772779"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media\/772778"}],"wp:attachment":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media?parent=772777"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/categories?post=772777"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/tags?post=772777"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}