{"id":761255,"date":"2025-09-17T23:58:21","date_gmt":"2025-09-17T21:58:21","guid":{"rendered":"https:\/\/www.hashtag.al\/?p=761255"},"modified":"2025-09-17T23:58:21","modified_gmt":"2025-09-17T21:58:21","slug":"aspirina-mund-te-ule-me-mbi-50-rikthimin-e-kancerit-kolorektal-te-disa-paciente","status":"publish","type":"post","link":"https:\/\/www.hashtag.al\/index.php\/2025\/09\/17\/aspirina-mund-te-ule-me-mbi-50-rikthimin-e-kancerit-kolorektal-te-disa-paciente\/","title":{"rendered":"Aspirina mund t\u00eb ul\u00eb me mbi 50% rikthimin e kancerit kolorektal te disa pacient\u00eb","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"

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\nNj\u00eb doz\u00eb e ul\u00ebt ditore e aspirines mund t\u00eb reduktoj\u00eb ndjesh\u00ebm rrezikun e rikthimit t\u00eb disa llojeve t\u00eb kancerit t\u00eb zorr\u00ebs s\u00eb trash\u00eb pas operacionit, sipas nj\u00eb studimi t\u00eb madh t\u00eb udh\u00ebhequr nga studiues suedez\u00eb, p\u00ebrcjell Guardian.<\/a><\/span><\/span><\/p>\n

Studiuesit n\u00eb Institutin Karolinska n\u00eb Stokholm zbuluan se pacient\u00ebt q\u00eb mor\u00ebn aspirin \u00e7do dit\u00eb pas heqjes s\u00eb tumorit kishin gjasa 50% m\u00eb t\u00eb ul\u00ebta q\u00eb kanceri t\u00eb rikthehej brenda tre viteve, krahasuar me ata q\u00eb mor\u00ebn nj\u00eb placebo.<\/span><\/p>\n

Ky efekt mbrojt\u00ebs u vu re te pacient\u00ebt q\u00eb kishin mutacione t\u00eb caktuara gjenetike q\u00eb i b\u00ebnin t\u00eb ndjesh\u00ebm ndaj vetive anti-kancer t\u00eb aspirines. Rreth 40% e pacient\u00ebve me kancer kolorektal mbajn\u00eb k\u00ebto mutacione.<\/span><\/p>\n

\u201cBesoj se k\u00ebto rezultate do t\u00eb ndryshojn\u00eb praktik\u00ebn klinike,\u201d u shpreh prof. Anna Martling, drejtuese e studimit ALASCCA. \u201cN\u00ebse keni k\u00ebto mutacione, rreziku q\u00eb kanceri t\u00eb rikthehet ulet me mbi 50%. Ky \u00ebsht\u00eb nj\u00eb efekt shum\u00eb i madh.\u201d<\/span><\/p>\n

\u00c7do vit, afro 2 milion\u00eb njer\u00ebz diagnostikohen me kancer kolorektal n\u00eb mbar\u00eb bot\u00ebn, p\u00ebrfshir\u00eb mbi 40 mij\u00eb raste n\u00eb Mbret\u00ebrin\u00eb e Bashkuar. Shum\u00eb pacient\u00eb i n\u00ebnshtrohen kirurgjis\u00eb p\u00ebr t\u00eb hequr tumorin, por pavar\u00ebsisht zhvillimeve n\u00eb kimioterapi dhe radioterapi, kanceri mund t\u00eb rikthehet n\u00ebse qelizat kancerogjene mbeten n\u00eb trup.<\/span><\/p>\n

P\u00ebrmes testimeve gjenetike, studiuesit identifikuan se 37% e pacient\u00ebve n\u00eb studim kishin mutacione n\u00eb rrug\u00ebn biologjike PI3K, e lidhur me zhvillimin e kancerit kolorektal. Pacient\u00ebt me k\u00ebto mutacione mor\u00ebn rast\u00ebsisht ose 160 mg aspirin n\u00eb dit\u00eb, ose nj\u00eb placebo p\u00ebr tre vite.<\/span><\/p>\n

Rezultatet treguan se ata q\u00eb mor\u00ebn aspirin kishin 55% m\u00eb pak gjasa q\u00eb kanceri t\u00eb rikthehej. Efekti i aspirines besohet t\u00eb vij\u00eb nga ndikimi i saj n\u00eb uljen e inflamacionit, nd\u00ebrhyrja n\u00eb rrug\u00ebn PI3K dhe frenimi i aktivitetit t\u00eb trombociteve t\u00eb gjakut, t\u00eb cilat mund t\u00eb ndihmojn\u00eb qelizat kancerogjene t\u00eb shmangin sistemin imunitar.<\/span><\/p>\n

Martling theksoi r\u00ebnd\u00ebsin\u00eb e testimeve gjenetike te t\u00eb gjith\u00eb pacient\u00ebt me kancer kolorektal, p\u00ebr t\u00eb identifikuar ata q\u00eb mund t\u00eb p\u00ebrfitojn\u00eb nga trajtimi me aspirin, nj\u00eb ila\u00e7 i lir\u00eb dhe i disponuesh\u00ebm gjer\u00ebsisht.<\/span><\/p>\n

Megjithat\u00eb, p\u00ebrdorimi afatgjat\u00eb i aspirines mbart rreziqe. N\u00eb k\u00ebt\u00eb studim, kat\u00ebr pacient\u00eb pat\u00ebn efekte an\u00ebsore serioze t\u00eb mundshme nga aspirina, p\u00ebrfshir\u00eb gjakderdhje n\u00eb stomak dhe tru, nd\u00ebrsa nj\u00eb vdekje u lidh potencialisht me p\u00ebrdorimin e saj. Detajet jan\u00eb publikuar n\u00eb New England Journal of Medicine<\/em>.<\/span><\/p>\n

Dr. Catherine Elliott nga Cancer Research UK tha: \u201cParandalimi i kancerit shp\u00ebton jet\u00eb, dhe gjetja e m\u00ebnyrave t\u00eb reja p\u00ebr ta b\u00ebr\u00eb k\u00ebt\u00eb \u00ebsht\u00eb thelb\u00ebsore. Ka gjithnj\u00eb e m\u00eb shum\u00eb d\u00ebshmi se, p\u00ebr disa grupe njer\u00ebzish, aspirina me doz\u00eb t\u00eb ul\u00ebt mund t\u00eb ofroj\u00eb mbrojtje kund\u00ebr kancerit t\u00eb zorr\u00ebs s\u00eb trash\u00eb.\u201d<\/span><\/p>\n

Ajo p\u00ebrmendi gjithashtu studimin CaPP3, i financuar nga Cancer Research UK, q\u00eb tregoi rezultate t\u00eb ngjashme te personat me sindrom\u00ebn e trash\u00ebguar Lynch.<\/span><\/p>\n

\u201cNa duhen studime m\u00eb t\u00eb m\u00ebdha dhe cil\u00ebsore, si CaPP3 dhe ky i fundit, p\u00ebr t\u00eb p\u00ebrcaktuar sakt\u00eb se kush p\u00ebrfiton m\u00eb shum\u00eb nga marrja e aspirines p\u00ebr t\u00eb jetuar jet\u00eb m\u00eb t\u00eb gjat\u00eb dhe m\u00eb t\u00eb mir\u00eb, pa frik\u00ebn e rikthimit t\u00eb kancerit,\u201d p\u00ebrfundoi ajo.<\/span><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"

Nj\u00eb doz\u00eb e ul\u00ebt ditore e aspirines mund t\u00eb reduktoj\u00eb ndjesh\u00ebm rrezikun e rikthimit t\u00eb disa llojeve t\u00eb kancerit t\u00eb zorr\u00ebs s\u00eb trash\u00eb pas operacionit, sipas nj\u00eb studimi t\u00eb madh t\u00eb udh\u00ebhequr nga studiues suedez\u00eb, p\u00ebrcjell Guardian. Studiuesit n\u00eb Institutin Karolinska n\u00eb Stokholm zbuluan se pacient\u00ebt q\u00eb mor\u00ebn aspirin \u00e7do dit\u00eb pas heqjes s\u00eb tumorit […]<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":32,"featured_media":761256,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[53],"tags":[],"class_list":["post-761255","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fast-foodi"],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/761255","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/users\/32"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/comments?post=761255"}],"version-history":[{"count":99999,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/761255\/revisions"}],"predecessor-version":[{"id":761257,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/761255\/revisions\/761257"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media\/761256"}],"wp:attachment":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media?parent=761255"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/categories?post=761255"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/tags?post=761255"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}