{"id":755806,"date":"2025-08-17T11:41:36","date_gmt":"2025-08-17T09:41:36","guid":{"rendered":"https:\/\/www.hashtag.al\/?p=755806"},"modified":"2025-08-17T11:44:14","modified_gmt":"2025-08-17T09:44:14","slug":"vaksina-kunder-kancerit-jep-shprese-ne-parandalimin-e-perseritjes-se-disa-tumoreve","status":"publish","type":"post","link":"https:\/\/www.hashtag.al\/index.php\/2025\/08\/17\/vaksina-kunder-kancerit-jep-shprese-ne-parandalimin-e-perseritjes-se-disa-tumoreve\/","title":{"rendered":"Vaksina kund\u00ebr kancerit jep shpres\u00eb n\u00eb parandalimin e p\u00ebrs\u00ebritjes s\u00eb disa tumoreve","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-755807\" src=\"https:\/\/www.hashtag.al\/wp-content\/uploads\/2025\/08\/colorectal-cancer-diagram-doctor-ezgif.com-webp-to-jpg-converter.jpg\" alt=\"\" width=\"1440\" height=\"810\" srcset=\"https:\/\/www.hashtag.al\/wp-content\/uploads\/2025\/08\/colorectal-cancer-diagram-doctor-ezgif.com-webp-to-jpg-converter.jpg 1440w, https:\/\/www.hashtag.al\/wp-content\/uploads\/2025\/08\/colorectal-cancer-diagram-doctor-ezgif.com-webp-to-jpg-converter-300x169.jpg 300w, https:\/\/www.hashtag.al\/wp-content\/uploads\/2025\/08\/colorectal-cancer-diagram-doctor-ezgif.com-webp-to-jpg-converter-1024x576.jpg 1024w, https:\/\/www.hashtag.al\/wp-content\/uploads\/2025\/08\/colorectal-cancer-diagram-doctor-ezgif.com-webp-to-jpg-converter-768x432.jpg 768w\" sizes=\"auto, (max-width: 1440px) 100vw, 1440px\" \/><\/p>\n<p><span style=\"color: #000000;\">Nj\u00eb vaksin\u00eb eksperimentale kund\u00ebr kancerit ka treguar premtime n\u00eb parandalimin e rikthimit t\u00eb disa llojeve t\u00eb kancerit.<\/span><\/p>\n<p><span style=\"color: #000000;\">N\u00eb nj\u00eb prov\u00eb klinike t\u00eb faz\u00ebs 1 t\u00eb udh\u00ebhequr pjes\u00ebrisht nga qendra e kancerit \u201cUCLA Health Jonsson\u201d, studiuesit testuan vaksin\u00ebn (ELI-002 2P) me 25 pacient\u00eb q\u00eb ishin trajtuar p\u00ebr kancer pankreatik dhe\u00a0kolorektal.<\/span><\/p>\n<p><span style=\"color: #000000;\">Pacient\u00ebt i ishin n\u00ebnshtruar t\u00eb gjith\u00eb nj\u00eb nd\u00ebrhyrjeje kirurgjikale p\u00ebr t\u00eb hequr tumoret dhe treguan &#8220;shenja t\u00eb s\u00ebmundjes minimale t\u00eb mbetur&#8221; ose gjurm\u00eb t\u00eb ADN-s\u00eb, duke i v\u00ebn\u00eb ata n\u00eb nj\u00eb rrezik t\u00eb lart\u00eb t\u00eb rikthimit, sipas nj\u00eb njoftimi p\u00ebr shtyp t\u00eb UCLA-s\u00eb.<\/span><\/p>\n<p><span style=\"color: #000000;\">M\u00eb shum\u00eb se 80% e pacient\u00ebve me kancer t\u00eb pankreasit p\u00ebrjetojn\u00eb rikthim t\u00eb s\u00ebmundjes pas operacionit, tregojn\u00eb studimet &#8211; dhe p\u00ebr 40% deri n\u00eb 50%, kjo ndodh brenda vitit t\u00eb par\u00eb.<\/span><\/p>\n<p><span style=\"color: #000000;\">P\u00ebr kancerin kolorektal, shkalla e rikthimit \u00ebsht\u00eb midis 30% dhe 50% dhe ka m\u00eb shum\u00eb t\u00eb ngjar\u00eb t\u00eb ndodh\u00eb brenda dy viteve t\u00eb para pas operacionit.<\/span><\/p>\n<p><span style=\"color: #000000;\">Mutacionet n\u00eb gjenin KRAS jan\u00eb p\u00ebrgjegj\u00ebse p\u00ebr gjysm\u00ebn e kancerit kolorektal dhe m\u00eb shum\u00eb se 90% t\u00eb kancerit t\u00eb pankreasit. Vaksina, e cila synon k\u00ebto mutacione, u dha n\u00ebp\u00ebrmjet nj\u00eb serie injeksionesh p\u00ebr t\u00eb aktivizuar nj\u00eb p\u00ebrgjigje imune n\u00eb nyjet limfatike.<\/span><\/p>\n<p><span style=\"color: #000000;\">Shumica (21 nga 25) e pacient\u00ebve prodhuan &#8220;qeliza T specifike p\u00ebr KRAS&#8221;, gj\u00eb q\u00eb tregon nj\u00eb p\u00ebrgjigje imune m\u00eb t\u00eb fort\u00eb. Studiuesit zbuluan se ato me p\u00ebrgjigje m\u00eb t\u00eb larta t\u00eb qelizave T treguan nj\u00eb mbijetes\u00eb m\u00eb t\u00eb gjat\u00eb pa rikthim krahasuar me ato me p\u00ebrgjigje m\u00eb t\u00eb ul\u00ebta.<\/span><\/p>\n<p><span style=\"color: #000000;\">P\u00ebr tre pacient\u00eb me kancer kolorektal dhe tre pacient\u00eb me kancer pankreatik, vaksina duket se i hoqi t\u00eb gjith\u00eb biomarkuesit e s\u00ebmundjes.<\/span><\/p>\n<p><span style=\"color: #000000;\">Nd\u00ebr pacient\u00ebt q\u00eb treguan p\u00ebrgjigjen m\u00eb t\u00eb fort\u00eb imune, shumica ishin ende pa kancer gati 20 muaj pas marrjes s\u00eb vaksin\u00ebs.<\/span><\/p>\n<p><span style=\"color: #000000;\">Gjetjet u botuan n\u00eb Nature Medicine.<\/span><\/p>\n<p><span style=\"color: #000000;\"><em><i>&#8220;Ky \u00ebsht\u00eb nj\u00eb p\u00ebrparim emocionues p\u00ebr pacient\u00ebt me kancer t\u00eb shkaktuar nga KRAS, ve\u00e7an\u00ebrisht kancerin e pankreasit, ku p\u00ebrs\u00ebritja pas trajtimit standard \u00ebsht\u00eb pothuajse e garantuar dhe terapit\u00eb efektive jan\u00eb t\u00eb kufizuara&#8221;<\/i><\/em>, tha autori i par\u00eb i studimit, Zev Wainberg, M.D., Profesor i Mjek\u00ebsis\u00eb n\u00eb Shkoll\u00ebn e Mjek\u00ebsis\u00eb \u201cDavid Geffen\u201d n\u00eb UCLA dhe studiues n\u00eb Qendr\u00ebn Gjith\u00ebp\u00ebrfshir\u00ebse t\u00eb Kancerit UCLA Health Jonsson, n\u00eb njoftim, shkruan <span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/www.foxnews.com\/health\/cancer-vaccine-shows-promise-preventing-recurrence-pancreatic-colorectal-tumors\">Fox<\/a><\/span>.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-755808\" src=\"https:\/\/www.hashtag.al\/wp-content\/uploads\/2025\/08\/vaksine.webp\" alt=\"\" width=\"1440\" height=\"810\" srcset=\"https:\/\/www.hashtag.al\/wp-content\/uploads\/2025\/08\/vaksine.webp 1440w, https:\/\/www.hashtag.al\/wp-content\/uploads\/2025\/08\/vaksine-300x169.webp 300w, https:\/\/www.hashtag.al\/wp-content\/uploads\/2025\/08\/vaksine-1024x576.webp 1024w, https:\/\/www.hashtag.al\/wp-content\/uploads\/2025\/08\/vaksine-768x432.webp 768w\" sizes=\"auto, (max-width: 1440px) 100vw, 1440px\" \/><\/p>\n<p><span style=\"color: #000000;\"><em><i>&#8220;Ne vum\u00eb re se pacient\u00ebt q\u00eb zhvilluan p\u00ebrgjigje t\u00eb forta imune ndaj vaksin\u00ebs mbet\u00ebn pa s\u00ebmundje dhe mbijetuan p\u00ebr shum\u00eb m\u00eb gjat\u00eb se sa pritej.&#8221;<\/i><\/em><\/span><\/p>\n<p><span style=\"color: #000000;\">N\u00eb nj\u00eb tjet\u00ebr gjetje, 67% e pacient\u00ebve n\u00eb prov\u00eb treguan p\u00ebrgjigje imune ndaj &#8220;mutacioneve shtes\u00eb t\u00eb shoq\u00ebruara me tumorin&#8221;, duke treguar se vaksina mund t\u00eb p\u00ebrdoret p\u00ebr t\u00eb shtypur &#8220;aktivitetin m\u00eb t\u00eb gjer\u00eb anti-tumor&#8221;.<\/span><\/p>\n<p><span style=\"color: #000000;\">Nj\u00eb nga p\u00ebrfitimet e ELI-002 2P, sipas studiuesve, \u00ebsht\u00eb se ajo konsiderohet &#8220;e gatshme p\u00ebr p\u00ebrdorim&#8221;, q\u00eb do t\u00eb thot\u00eb se \u00ebsht\u00eb nj\u00eb vaksin\u00eb e prodhuar n\u00eb mas\u00eb, e standardizuar q\u00eb nuk ka nevoj\u00eb t\u00eb personalizohet p\u00ebr secilin pacient individual.<\/span><\/p>\n<p><span style=\"color: #000000;\"><em><i>&#8220;Ky studim tregon se vaksina ELI-002 2P mund ta st\u00ebrvit\u00eb n\u00eb m\u00ebnyr\u00eb t\u00eb sigurt dhe efektive sistemin imunitar p\u00ebr t\u00eb njohur dhe luftuar mutacionet q\u00eb shkaktojn\u00eb kancerin&#8221;<\/i><\/em>, tha Wainberg.<\/span><\/p>\n<p><span style=\"color: #000000;\"><em><i>&#8220;Ofron nj\u00eb qasje premtuese p\u00ebr t\u00eb <\/i><\/em><em><i>prodhuar <\/i><\/em><em><i>p\u00ebrgjigje imune t\u00eb sakta dhe t\u00eb q\u00ebndrueshme pa kompleksitetin ose koston e vaksinave plot\u00ebsisht t\u00eb personalizuara.&#8221;<\/i><\/em><\/span><\/p>\n<p><span style=\"color: #000000;\">Ekipi ka p\u00ebrfunduar tashm\u00eb regjistrimin e pjes\u00ebmarr\u00ebsve p\u00ebr nj\u00eb studim t\u00eb faz\u00ebs 2 q\u00eb do testoj\u00eb ELI-002 7P, versionin e ardhsh\u00ebm t\u00eb vaksin\u00ebs q\u00eb do t\u00eb synoj\u00eb nj\u00eb &#8220;grup m\u00eb t\u00eb gjer\u00eb&#8221; mutacionesh KRAS, thuhet n\u00eb njoftim.<\/span><\/p>\n<p><span style=\"color: #000000;\">Studimi u sponsorizua dhe u financua nga Elicio Therapeutics, kompania nga Massachusetts q\u00eb zhvilloi vaksin\u00ebn.<\/span><\/p>\n<p><span style=\"color: #000000;\">U krye n\u00eb bashk\u00ebpunim me Qendr\u00ebn e Kancerit MD Anderson dhe Qendr\u00ebn e Kancerit Memorial Sloan Kettering.<\/span><\/p>\n<p><span style=\"color: #000000;\">Dr. Marc Siegel, analist i lart\u00eb mjek\u00ebsor i Fox Ne\u00ebs, nuk ishte i p\u00ebrfshir\u00eb n\u00eb studim, por komentoi se terapit\u00eb e synuara po b\u00ebhen mjete gjithnj\u00eb e m\u00eb t\u00eb r\u00ebnd\u00ebsishme n\u00eb luft\u00ebn kund\u00ebr kancerit.<\/span><\/p>\n<p><span style=\"color: #000000;\"><em><i>&#8220;Tumoret e ngurta, ve\u00e7an\u00ebrisht ato pankreatike, mund t\u00eb jen\u00eb t\u00eb v\u00ebshtira p\u00ebr t&#8217;u trajtuar sepse nuk jan\u00eb aq mutagjene (t\u00eb afta p\u00ebr t\u00eb nxitur ose shkaktuar mutacione) sa tumoret malinje hematologjike (kanceret e gjakut) ose melanoma, p\u00ebr shembull, k\u00ebshtu q\u00eb ato nuk kan\u00eb aq shum\u00eb objektiva t\u00eb gatsh\u00ebm p\u00ebr imunoterapi&#8221;<\/i><\/em>, tha ai p\u00ebr Fox Ne\u00ebs.<\/span><\/p>\n<p><span style=\"color: #000000;\"><em><i>&#8220;Vaksina e re kund\u00ebr kancerit nga UCLA \u00ebsht\u00eb shum\u00eb premtuese si nj\u00eb mjet i r\u00ebnd\u00ebsish\u00ebm kund\u00ebr k\u00ebtyre kancereve, pasi &#8216;programon&#8217; sistemin imunitar p\u00ebr t\u00eb synuar k\u00ebto mutacione dhe \u00ebsht\u00eb treguar n\u00eb studimin NATURE se shkakton nj\u00eb p\u00ebrgjigje t\u00eb fort\u00eb klinike.&#8221;<\/i><\/em><\/span><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>Nj\u00eb vaksin\u00eb eksperimentale kund\u00ebr kancerit ka treguar premtime n\u00eb parandalimin e rikthimit t\u00eb disa llojeve t\u00eb kancerit. N\u00eb nj\u00eb prov\u00eb klinike t\u00eb faz\u00ebs 1 t\u00eb udh\u00ebhequr pjes\u00ebrisht nga qendra e kancerit \u201cUCLA Health Jonsson\u201d, studiuesit testuan vaksin\u00ebn (ELI-002 2P) me 25 pacient\u00eb q\u00eb ishin trajtuar p\u00ebr kancer pankreatik dhe\u00a0kolorektal. Pacient\u00ebt i ishin n\u00ebnshtruar t\u00eb gjith\u00eb [&hellip;]<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":51,"featured_media":755807,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[53],"tags":[],"class_list":["post-755806","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fast-foodi"],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/755806","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/users\/51"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/comments?post=755806"}],"version-history":[{"count":3,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/755806\/revisions"}],"predecessor-version":[{"id":755812,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/755806\/revisions\/755812"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media\/755807"}],"wp:attachment":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media?parent=755806"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/categories?post=755806"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/tags?post=755806"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}