{"id":653705,"date":"2024-02-12T23:59:22","date_gmt":"2024-02-12T22:59:22","guid":{"rendered":"https:\/\/www.hashtag.al\/?p=653705"},"modified":"2024-02-12T23:59:22","modified_gmt":"2024-02-12T22:59:22","slug":"proteinat-mund-te-parashikojne-se-kush-do-te-kete-demence-10-vjet-me-vone-studimi","status":"publish","type":"post","link":"https:\/\/www.hashtag.al\/index.php\/2024\/02\/12\/proteinat-mund-te-parashikojne-se-kush-do-te-kete-demence-10-vjet-me-vone-studimi\/","title":{"rendered":"Proteinat mund t\u00eb parashikojn\u00eb se kush do t\u00eb ket\u00eb demenc\u00eb 10 vjet m\u00eb von\u00eb – Studimi","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"

\"\"<\/a><\/span><\/p>\n

Nj\u00eb studim i mostrave t\u00eb gjakut t\u00eb ngrir\u00eb ka zbuluar nj\u00eb grumbull proteinash q\u00eb mund t\u00eb parashikojn\u00eb disa forma t\u00eb demenc\u00ebs m\u00eb shum\u00eb se 10 vjet p\u00ebrpara se s\u00ebmundja t\u00eb diagnostikohet, raportuan t\u00eb h\u00ebn\u00ebn studiuesit nga Britania e Madhe dhe Kina.<\/span><\/p>\n

Studimi, i botuar n\u00eb revist\u00ebn Nature Aging, hap nj\u00eb sked\u00eb t\u00eb re, \u00ebsht\u00eb pjes\u00eb e k\u00ebrkimit t\u00eb vazhduesh\u00ebm nga ekipe t\u00eb shumta p\u00ebr t\u00eb identifikuar pacient\u00ebt n\u00eb rrezik p\u00ebr demenc\u00eb duke p\u00ebrdorur nj\u00eb test t\u00eb thjesht\u00eb gjaku, nj\u00eb p\u00ebrparim q\u00eb shum\u00eb shkenc\u00ebtar\u00eb besojn\u00eb se do t\u00eb p\u00ebrshpejtoj\u00eb zhvillimin e trajtimeve t\u00eb reja, p\u00ebrcjell Reuters.<\/a><\/span><\/span><\/p>\n

Aktualisht, skanimet e trurit mund t\u00eb zbulojn\u00eb nivele jonormale t\u00eb nj\u00eb proteine t\u00eb quajtur beta amiloid shum\u00eb vite p\u00ebrpara se t\u00eb zhvillohet demenca e Alzheimerit, por testet jan\u00eb t\u00eb kushtueshme dhe shpesh nuk mbulohen nga sigurimet.<\/span><\/p>\n

“Bazuar n\u00eb k\u00ebt\u00eb studim, duket se do t\u00eb zhvillohen teste gjaku q\u00eb mund t\u00eb parashikojn\u00eb rrezikun p\u00ebr zhvillimin e demenc\u00ebs gjat\u00eb 10 viteve t\u00eb ardhshme, megjith\u00ebse individ\u00ebt me rrezik m\u00eb t\u00eb lart\u00eb shpesh kan\u00eb v\u00ebshtir\u00ebsi t\u00eb din\u00eb se si t\u00eb p\u00ebrgjigjen,”<\/em> tha Dr. Suzanne Schindler, nj\u00eb. Studiues i Alzheimerit n\u00eb Universitetin e Uashingtonit n\u00eb St. Louis, i cili nuk ishte i p\u00ebrfshir\u00eb n\u00eb hulumtim.<\/span><\/p>\n

Autori i studimit Jian-Feng Feng i Universitetit Fudan n\u00eb Shangai tha se teste t\u00eb tilla jan\u00eb kritike n\u00eb popullatat e plakjes si ajo e Kin\u00ebs, dhe vuri n\u00eb dukje se ai \u00ebsht\u00eb n\u00eb bisedime p\u00ebr zhvillimin e mundsh\u00ebm komercial t\u00eb nj\u00eb testi gjaku bazuar n\u00eb k\u00ebrkimin e tyre.<\/span><\/p>\n

N\u00eb studim, studiuesit n\u00eb Universitetin e Warwick dhe Universitetin Fudan studiuan 52,645 mostra gjaku nga depoja e k\u00ebrkimit t\u00eb Biobank n\u00eb Mbret\u00ebrin\u00eb e Bashkuar, t\u00eb mbledhura midis 2006 dhe 2010 nga njer\u00ebz q\u00eb nuk kishin shenja t\u00eb demenc\u00ebs n\u00eb at\u00eb koh\u00eb.<\/span><\/p>\n

Nga k\u00ebta, 1,417 njer\u00ebz p\u00ebrfundimisht zhvilluan s\u00ebmundjen e Alzheimerit, \u00e7menduri vaskulare ose \u00e7menduri nga \u00e7do shkak. Studiuesit studiuan n\u00ebnshkrimet e proteinave t\u00eb zakonshme tek k\u00ebta individ\u00eb dhe zbuluan 1,463 proteina t\u00eb lidhura me demenc\u00ebn dhe i rendit\u00ebn ato sipas mund\u00ebsive q\u00eb ata t\u00eb parashikonin \u00e7mendurin\u00eb.<\/span><\/p>\n

Ata zbuluan se njer\u00ebzit gjaku i t\u00eb cil\u00ebve mbante nivele m\u00eb t\u00eb larta t\u00eb proteinave GFAP, NEFL, GDF15 dhe LTBP2 kishin vazhdimisht m\u00eb shum\u00eb gjasa t\u00eb kishin zhvilluar s\u00ebmundjen e Alzheimerit, \u00e7menduri vaskulare ose \u00e7menduri nga \u00e7far\u00ebdo shkaku. Njer\u00ebzit me nivele t\u00eb larta t\u00eb GFAP kishin 2.32 her\u00eb m\u00eb shum\u00eb gjasa p\u00ebr t\u00eb zhvilluar demenc\u00eb, duke konfirmuar gjetjet nga studimet m\u00eb t\u00eb vogla q\u00eb kishin treguar p\u00ebr kontributin e k\u00ebsaj proteine.<\/span><\/p>\n

Autor\u00ebt vun\u00eb n\u00eb dukje se k\u00ebrkimi i tyre nuk \u00ebsht\u00eb v\u00ebrtetuar n\u00eb m\u00ebnyr\u00eb t\u00eb pavarur.<\/span><\/p>\n

Nj\u00eb protein\u00eb q\u00eb performoi mir\u00eb n\u00eb parashikimin e demenc\u00ebs, drita e neurofilamentit, p\u00ebrdoret tashm\u00eb n\u00eb klinik\u00eb p\u00ebr diagnostikimin dhe monitorimin e disa kushteve si skleroza e shum\u00ebfisht\u00eb, tha Schindler n\u00eb nj\u00eb email.<\/span><\/p>\n

“Ky studim nuk p\u00ebrfshinte teste gjaku t\u00eb disponueshme klinikisht p\u00ebr s\u00ebmundjen Alzheimer, t\u00eb cilat ka t\u00eb ngjar\u00eb t\u00eb parashikojn\u00eb edhe m\u00eb mir\u00eb zhvillimin e demenc\u00ebs p\u00ebr shkak t\u00eb s\u00ebmundjes Alzheimer<\/em>,” tha ajo.<\/span><\/p>\n

Teste t\u00eb tilla tashm\u00eb jan\u00eb duke u p\u00ebrdorur n\u00eb identifikimin e kandidat\u00ebve p\u00ebr provat klinike q\u00eb testojn\u00eb trajtime n\u00eb pacient\u00ebt me s\u00ebmundje t\u00eb faz\u00ebs s\u00eb hershme apo edhe presimptomatike, si Eisai (4523.T), hap nj\u00eb sked\u00eb t\u00eb re dhe Biogen’s (BIIB.O), hap sked\u00eb t\u00eb re Leqembi. Ila\u00e7i s\u00eb fundmi fitoi miratimin rregullator n\u00eb Shtetet e Bashkuara, Japoni dhe Kin\u00eb.<\/span><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"

Nj\u00eb studim i mostrave t\u00eb gjakut t\u00eb ngrir\u00eb ka zbuluar nj\u00eb grumbull proteinash q\u00eb mund t\u00eb parashikojn\u00eb disa forma t\u00eb demenc\u00ebs m\u00eb shum\u00eb se 10 vjet p\u00ebrpara se s\u00ebmundja t\u00eb diagnostikohet, raportuan t\u00eb h\u00ebn\u00ebn studiuesit nga Britania e Madhe dhe Kina. Studimi, i botuar n\u00eb revist\u00ebn Nature Aging, hap nj\u00eb sked\u00eb t\u00eb re, \u00ebsht\u00eb pjes\u00eb […]<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":30,"featured_media":653706,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[53],"tags":[],"class_list":["post-653705","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fast-foodi"],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/653705","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/users\/30"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/comments?post=653705"}],"version-history":[{"count":0,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/653705\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media\/653706"}],"wp:attachment":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media?parent=653705"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/categories?post=653705"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/tags?post=653705"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}