{"id":651574,"date":"2024-02-04T19:50:44","date_gmt":"2024-02-04T18:50:44","guid":{"rendered":"https:\/\/www.hashtag.al\/?p=651574"},"modified":"2024-02-04T19:51:14","modified_gmt":"2024-02-04T18:51:14","slug":"pacientet-e-pare-ne-mbreterine-e-bashkuar-marrin-terapi-eksperimentale-te-kancerit-me-mesazher-arn","status":"publish","type":"post","link":"https:\/\/www.hashtag.al\/index.php\/2024\/02\/04\/pacientet-e-pare-ne-mbreterine-e-bashkuar-marrin-terapi-eksperimentale-te-kancerit-me-mesazher-arn\/","title":{"rendered":"Pacient\u00ebt e par\u00eb n\u00eb Mbret\u00ebrin\u00eb e Bashkuar marrin terapi eksperimentale t\u00eb kancerit me mesazher ARN","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"

\"\"<\/a><\/span><\/p>\n

Nj\u00eb trajtim i ri revolucionar i kancerit i njohur si terapi mRNA u \u00ebsht\u00eb administruar pacient\u00ebve n\u00eb spitalin Hammersmith n\u00eb per\u00ebndim t\u00eb Londr\u00ebs.<\/span><\/p>\n

Testi \u00ebsht\u00eb krijuar p\u00ebr t\u00eb vler\u00ebsuar sigurin\u00eb dhe efektivitetin e terapis\u00eb n\u00eb trajtimin e melanom\u00ebs, kancerit t\u00eb mushk\u00ebrive dhe tumoreve t\u00eb tjera t\u00eb ngurta.<\/span><\/p>\n

Trajtimi i ri p\u00ebrdor materialin gjenetik t\u00eb njohur si ARN mesazhere, ose mRNA dhe funksionon duke paraqitur sh\u00ebnues t\u00eb zakonsh\u00ebm nga tumoret n\u00eb sistemin imunitar t\u00eb pacientit, p\u00ebrcjell The Guardian.<\/a><\/span><\/span><\/p>\n

Q\u00ebllimi \u00ebsht\u00eb ta ndihmoj\u00eb at\u00eb t\u00eb njoh\u00eb dhe t\u00eb luftoj\u00eb qelizat kancerogjene q\u00eb shprehin ata sh\u00ebnues.<\/span><\/p>\n

“Imunoterapit\u00eb e reja t\u00eb kancerit t\u00eb bazuara n\u00eb mRNA ofrojn\u00eb nj\u00eb rrug\u00eb p\u00ebr rekrutimin e sistemit imunitar t\u00eb pacientit p\u00ebr t\u00eb luftuar kancerin e tyre,”<\/em> tha Dr David Pinato nga Imperial College London, nj\u00eb hetues me krahun e prov\u00ebs n\u00eb Mbret\u00ebrin\u00eb e Bashkuar.<\/span><\/p>\n

Pinato tha se ky hulumtim ishte ende n\u00eb fazat e tij t\u00eb hershme dhe mund t\u00eb duheshin vite p\u00ebrpara se t\u00eb b\u00ebhej i disponuesh\u00ebm p\u00ebr pacient\u00ebt. Megjithat\u00eb, prova e re po vendoste bazat thelb\u00ebsore q\u00eb mund t\u00eb ndihmonin n\u00eb zhvillimin e terapive t\u00eb reja m\u00eb pak toksike dhe m\u00eb t\u00eb sakta kund\u00ebr kancerit. “Ne kemi nevoj\u00eb d\u00ebshp\u00ebrimisht p\u00ebr k\u00ebto p\u00ebr t\u00eb kthyer val\u00ebn kund\u00ebr kancerit,”<\/em> shtoi ai.<\/span><\/p>\n

Nj\u00eb num\u00ebr i vaksinave kund\u00ebr kancerit kan\u00eb hyr\u00eb koh\u00ebt e fundit n\u00eb provat klinike n\u00eb t\u00eb gjith\u00eb globin. K\u00ebto ndahen n\u00eb dy kategori: imunoterapi t\u00eb personalizuara t\u00eb kancerit, t\u00eb cilat mb\u00ebshteten n\u00eb nxjerrjen e materialit gjenetik t\u00eb pacientit nga tumoret e tyre; dhe imunoterapit\u00eb terapeutike t\u00eb kancerit, t\u00eb tilla si terapia mRNA e sapolan\u00e7uar n\u00eb Lond\u00ebr, t\u00eb cilat jan\u00eb “t\u00eb gatshme” dhe t\u00eb p\u00ebrshtatura p\u00ebr nj\u00eb lloj t\u00eb ve\u00e7ant\u00eb kanceri.<\/span><\/p>\n

Q\u00ebllimi kryesor i prov\u00ebs s\u00eb re – i njohur si Mobilize – \u00ebsht\u00eb t\u00eb zbuloj\u00eb n\u00ebse ky lloj i ve\u00e7ant\u00eb i terapis\u00eb me mRNA \u00ebsht\u00eb i sigurt dhe i toleruar nga pacient\u00ebt me kancer t\u00eb mushk\u00ebrive ose l\u00ebkur\u00ebs dhe mund t\u00eb tkurr tumoret. Ai do t\u00eb administrohet vet\u00ebm n\u00eb disa raste dhe n\u00eb kombinim me ila\u00e7in ekzistues t\u00eb kancerit pembrolizumab n\u00eb t\u00eb tjera.<\/span><\/p>\n

Studiuesit thon\u00eb se nd\u00ebrsa terapia eksperimentale \u00ebsht\u00eb ende n\u00eb fazat e hershme t\u00eb testimit, ata shpresojn\u00eb se p\u00ebrfundimisht mund t\u00eb \u00e7oj\u00eb n\u00eb nj\u00eb opsion t\u00eb ri trajtimi p\u00ebr kanceret e v\u00ebshtira p\u00ebr t’u trajtuar, n\u00ebse qasja provohet t\u00eb jet\u00eb e sigurt dhe efektive.<\/span><\/p>\n

Gati nj\u00eb n\u00eb dy njer\u00ebz n\u00eb Mbret\u00ebrin\u00eb e Bashkuar do t\u00eb diagnostikohet me kancer gjat\u00eb jet\u00ebs s\u00eb tyre. Nj\u00eb s\u00ebr\u00eb terapish jan\u00eb zhvilluar p\u00ebr trajtimin e pacient\u00ebve, duke p\u00ebrfshir\u00eb kimioterapin\u00eb dhe terapit\u00eb imune.<\/span><\/p>\n

Megjithat\u00eb, qelizat e kancerit mund t\u00eb b\u00ebhen rezistente ndaj ila\u00e7eve, duke i b\u00ebr\u00eb tumoret m\u00eb t\u00eb v\u00ebshtira p\u00ebr t’u trajtuar dhe shkenc\u00ebtar\u00ebt jan\u00eb t\u00eb prirur t\u00eb k\u00ebrkojn\u00eb qasje t\u00eb reja p\u00ebr trajtimin e kancerit.<\/span><\/p>\n

Testimi paraklinik n\u00eb modelet qelizore dhe shtazore t\u00eb kancerit siguroi prova se terapia e re mRNA kishte nj\u00eb efekt n\u00eb sistemin imunitar dhe mund t’u ofrohej pacient\u00ebve n\u00eb provat klinike t\u00eb faz\u00ebs s\u00eb hershme.<\/span><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"

Nj\u00eb trajtim i ri revolucionar i kancerit i njohur si terapi mRNA u \u00ebsht\u00eb administruar pacient\u00ebve n\u00eb spitalin Hammersmith n\u00eb per\u00ebndim t\u00eb Londr\u00ebs. Testi \u00ebsht\u00eb krijuar p\u00ebr t\u00eb vler\u00ebsuar sigurin\u00eb dhe efektivitetin e terapis\u00eb n\u00eb trajtimin e melanom\u00ebs, kancerit t\u00eb mushk\u00ebrive dhe tumoreve t\u00eb tjera t\u00eb ngurta. Trajtimi i ri p\u00ebrdor materialin gjenetik t\u00eb njohur […]<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":30,"featured_media":651575,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-651574","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nderkombetare"],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/651574","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/users\/30"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/comments?post=651574"}],"version-history":[{"count":0,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/651574\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media\/651575"}],"wp:attachment":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media?parent=651574"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/categories?post=651574"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/tags?post=651574"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}