{"id":379904,"date":"2020-06-10T17:55:16","date_gmt":"2020-06-10T15:55:16","guid":{"rendered":"https:\/\/hashtag.al\/?p=379904"},"modified":"2020-06-10T17:44:33","modified_gmt":"2020-06-10T15:44:33","slug":"zbulimi-shkencetaret-rigjenerojne-nje-proteine-qe-lufton-kancerin-e-riparon-neuronet-e-demtuara","status":"publish","type":"post","link":"https:\/\/www.hashtag.al\/index.php\/2020\/06\/10\/zbulimi-shkencetaret-rigjenerojne-nje-proteine-qe-lufton-kancerin-e-riparon-neuronet-e-demtuara\/","title":{"rendered":"Zbulimi – Shkenc\u00ebtar\u00ebt rigjenerojn\u00eb nj\u00eb protein\u00eb q\u00eb lufton kancerin e riparon neuronet e d\u00ebmtuara","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"

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Studiuesit kan\u00eb b\u00ebr\u00eb nj\u00eb p\u00ebrparim t\u00eb ri duke p\u00ebrdorur proteina t\u00eb rigjeneruara p\u00ebr t\u00eb \u2018zhbllokuar\u2019 aft\u00ebsit\u00eb brenda trupit t\u00eb njeriut, t\u00eb cilat mund t\u00eb ndalojn\u00eb rritjen e kancerit dhe madje mund t\u00eb rigjenerojn\u00eb neuronet e d\u00ebmtuara.<\/span><\/p>\n

Bioinxhinierja e Universitetit t\u00eb Stanfordit, Jennifer Cochran, ka shpenzuar vite t\u00eb t\u00ebra duke studiuar dhe rigjeneruar lajm\u00ebtar\u00ebt e proteinave t\u00eb njohur si ligand\u00eb.<\/span><\/p>\n

Ligandet rregullojn\u00eb proceset biologjike n\u00eb mushk\u00ebrit\u00eb, kockat, en\u00ebt e gjakut dhe organet e tjera kryesore, prandaj jan\u00eb thelb\u00ebsore p\u00ebr luft\u00ebn kund\u00ebr shumic\u00ebs s\u00eb s\u00ebmundjeve q\u00eb pllakosin njer\u00ebzimin. <\/span><\/p>\n

Duke u bazuar n\u00eb hulumtimet e p\u00ebrfunduara n\u00eb vitin 2019, Cochran dhe koleg\u00ebt e saj projektuan me sukses nj\u00eb ligand p\u00ebr t\u00eb prodhuar dy rezultate shum\u00eb t\u00eb ndryshme por po aq t\u00eb r\u00ebnd\u00ebsishme: Nj\u00eb shkaktoi q\u00eb qelizat neuronale t\u00eb rigjenerohen nd\u00ebrsa ndryshimet e vogla n\u00eb t\u00eb nj\u00ebjt\u00ebn protein\u00eb penguan rritjen e tumorit t\u00eb mushk\u00ebrive.<\/span><\/p>\n

Nd\u00ebrsa hulumtimi \u00ebsht\u00eb kryer vet\u00ebm n\u00eb qelizat njer\u00ebzore dhe ato t\u00eb minjve n\u00eb kushte laboratorike, ekipi shpreson se mund t\u00eb revolucionarizoj\u00eb aft\u00ebsin\u00eb ton\u00eb p\u00ebr t\u00eb trajtuar nj\u00eb s\u00ebr\u00eb s\u00ebmundjesh.<\/span><\/p>\n

“K\u00ebto proteina mund t\u00eb shpresojm\u00eb q\u00eb nj\u00eb dit\u00eb t\u00eb p\u00ebrdoren p\u00ebr t\u00eb trajtuar s\u00ebmundjet neurodegjeneruese, kanceret dhe \u00e7rregullime t\u00eb tjera t\u00eb tilla si osteoporoza dhe arterioskleroza”<\/em>, tha Cochran.<\/span><\/p>\n

Ligandet dhe receptor\u00ebt punojn\u00eb n\u00eb simfoni p\u00ebr t\u00eb d\u00ebrguar mesazhe n\u00eb qeliza dhe duke projektuar me kujdes format e ligand\u00ebve, shkenc\u00ebtar\u00ebt mund t\u00eb efektet e fuqishme terapeutike brenda trupit ton\u00eb.<\/span><\/p>\n

Duke p\u00ebrdorur teknika t\u00eb sofistikuara t\u00eb inxhinieris\u00eb molekulare, studiuesit mund t\u00eb nd\u00ebrtojn\u00eb miliona \u2018\u00e7el\u00ebsa\u2019 biologjik\u00eb duke riorganizuar aminoacidet t\u00eb cil\u00ebt p\u00ebrb\u00ebjn\u00eb nj\u00eb ligand t\u00eb caktuar dhe m\u00eb pas t\u00eb testojn\u00eb secilin individualisht p\u00ebr t\u00eb zbuluar se si t\u00eb zhbllokojn\u00eb receptor\u00eb t\u00eb caktuar dhe t\u00eb arrijn\u00eb rezultate t\u00eb jasht\u00ebzakonshme si nd\u00ebrtimi i qelizave m\u00eb t\u00eb forta ose kufizimi i rritjes s\u00eb qelizave tumorale.<\/span><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"

Studiuesit kan\u00eb b\u00ebr\u00eb nj\u00eb p\u00ebrparim t\u00eb ri duke p\u00ebrdorur proteina t\u00eb rigjeneruara p\u00ebr t\u00eb \u2018zhbllokuar\u2019 aft\u00ebsit\u00eb brenda trupit t\u00eb njeriut, t\u00eb cilat mund t\u00eb ndalojn\u00eb rritjen e kancerit dhe madje mund t\u00eb rigjenerojn\u00eb neuronet e d\u00ebmtuara. Bioinxhinierja e Universitetit t\u00eb Stanfordit, Jennifer Cochran, ka shpenzuar vite t\u00eb t\u00ebra duke studiuar dhe rigjeneruar lajm\u00ebtar\u00ebt e proteinave […]<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":51,"featured_media":379905,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[53],"tags":[],"class_list":["post-379904","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fast-foodi"],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/379904","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/users\/51"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/comments?post=379904"}],"version-history":[{"count":0,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/379904\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media\/379905"}],"wp:attachment":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media?parent=379904"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/categories?post=379904"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/tags?post=379904"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}