{"id":308119,"date":"2019-07-04T13:20:00","date_gmt":"2019-07-04T11:20:00","guid":{"rendered":"https:\/\/hashtag.al\/?p=308119"},"modified":"2019-07-04T13:21:33","modified_gmt":"2019-07-04T11:21:33","slug":"shkencetaret-kurojne-hiv-in-te-minjte-per-here-te-pare","status":"publish","type":"post","link":"https:\/\/www.hashtag.al\/index.php\/2019\/07\/04\/shkencetaret-kurojne-hiv-in-te-minjte-per-here-te-pare\/","title":{"rendered":"Shkenc\u00ebtar\u00ebt kurojn\u00eb HIV-in te minjt\u00eb p\u00ebr her\u00eb t\u00eb par\u00eb","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"

\"\"<\/p>\n

Nj\u00eb grup shkenc\u00ebtar\u00ebsh, kan\u00eb eliminuar p\u00ebr her\u00eb t\u00eb par\u00eb ADN-n\u00eb e HIV-it nga gjenet e kafsh\u00ebve t\u00eb gjalla, n\u00eb at\u00eb q\u00eb p\u00ebrshkruhet si nj\u00eb hap tejet i r\u00ebnd\u00ebsish\u00ebm drejt zhvillimit t\u00eb nj\u00eb kure p\u00ebr virusin AIDS.<\/span><\/p>\n

Studimi novator, i botuar n\u00eb revist\u00ebn \u2018Nature Communications\u2019, zbuloi se trajtimi p\u00ebr t\u00eb shtypur shtimin e HIV-it s\u00eb bashku me terapin\u00eb e reduktimit t\u00eb gjeneve mund t\u00eb eliminoj\u00eb HIV-in nga qelizat dhe organet e infektuara.<\/span><\/p>\n

Trajtimi i tanish\u00ebm i HIV-it p\u00ebrqendrohet n\u00eb p\u00ebrdorimin gjith\u00ebp\u00ebrfshir\u00ebs t\u00eb terapis\u00eb antiretrovirale (ART), e cila shtyp shtimin e HIV-it, por nuk eliminon virusin. <\/span><\/p>\n

Dr. Kamel Khalili, nj\u00eb nga k\u00ebrkuesit kryesor\u00eb t\u00eb studimit, kishte gjetur n\u00eb pun\u00ebn e m\u00ebparshme q\u00eb duke p\u00ebrdorur teknologjin\u00eb CRISPR-Cas9 t\u00eb korrigjimit s\u00eb gjeneve, fragmente t\u00eb m\u00ebdha t\u00eb ADN-s\u00eb s\u00eb HIV-it mund t\u00eb hiqen nga qelizat e infektuara.<\/span><\/p>\n

P\u00ebr studimin e ri, Khalili dhe koleg\u00ebt e tij kombinuan sistemin e korrigjimit t\u00eb gjeneve me nj\u00eb strategji terapeutike t\u00eb zhvilluar koh\u00ebt e fundit, e njohur si ART (LASER) me funksion t\u00eb veprimit t\u00eb vonuar me efekt t\u00eb ngadalt\u00eb. <\/span><\/p>\n

LASER kufizon shtimin e HIV-it n\u00eb nivele t\u00eb ul\u00ebta p\u00ebr periudha t\u00eb zgjatura kohore, potencialisht duke lejuar koh\u00ebn p\u00ebr faz\u00ebn e korrigjimit t\u00eb gjenit t\u00eb prov\u00ebs p\u00ebr t\u00eb nisur.<\/span><\/p>\n

Ila\u00e7i i sapo modifikuar u paketua n\u00eb nanokristale, t\u00eb cilat mund t\u00eb d\u00ebrgohen n\u00eb indet e infektuara me HIV dhe lirimin ngadal\u00eb t\u00eb ila\u00e7it p\u00ebr disa jav\u00eb.<\/span><\/p>\n

Hulumtuesit pastaj p\u00ebrdor\u00ebn nj\u00eb kombinim t\u00eb LASER ART dhe CRISPR-Cas9 p\u00ebr trajtimin e minjve t\u00eb projektuara posa\u00e7\u00ebrisht p\u00ebr t\u00eb prodhuar qeliza njer\u00ebzore t\u00eb prekshme ndaj HIV. <\/span><\/p>\n

Ve\u00e7an\u00ebrisht, rezultatet treguan nj\u00eb eliminim t\u00eb plot\u00eb t\u00eb ADN-s\u00eb s\u00eb HIV-it n\u00eb rreth nj\u00eb t\u00eb tret\u00ebn e minjve t\u00eb infektuar me HIV, sipas ekipit.<\/span><\/p>\n

Dr Ho\u00ebard Gendelman, bashk\u00eb-udh\u00ebheq\u00ebs i studimit, tha se hulumtuesit tani kan\u00eb nj\u00eb \u2018rrug\u00eb t\u00eb qart\u00eb p\u00ebr t\u00eb ecur p\u00ebrpara n\u00eb testet n\u00eb primatet jo njer\u00ebzore dhe ndoshta n\u00eb testet klinike n\u00eb pacient\u00ebt e njeriut brenda vitit\u2019<\/em>.<\/span><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"

Nj\u00eb grup shkenc\u00ebtar\u00ebsh, kan\u00eb eliminuar p\u00ebr her\u00eb t\u00eb par\u00eb ADN-n\u00eb e HIV-it nga gjenet e kafsh\u00ebve t\u00eb gjalla, n\u00eb at\u00eb q\u00eb p\u00ebrshkruhet si nj\u00eb hap tejet i r\u00ebnd\u00ebsish\u00ebm drejt zhvillimit t\u00eb nj\u00eb kure p\u00ebr virusin AIDS. Studimi novator, i botuar n\u00eb revist\u00ebn \u2018Nature Communications\u2019, zbuloi se trajtimi p\u00ebr t\u00eb shtypur shtimin e HIV-it s\u00eb bashku […]<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":51,"featured_media":308120,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-308119","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nderkombetare"],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/308119","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/users\/51"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/comments?post=308119"}],"version-history":[{"count":0,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/posts\/308119\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media\/308120"}],"wp:attachment":[{"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/media?parent=308119"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/categories?post=308119"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hashtag.al\/index.php\/wp-json\/wp\/v2\/tags?post=308119"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}